Mitral valve infective endocarditis as a manifestation of disseminatedCryptococcus neoformans infection: a case report

Oyuky Flores-Alamos; Diego González-Guzmán; Antonio de Jesús Andrade-Ortega; Jaime Ponce-Gallegos; Amayrani E. Coyac-Cavazos; César Yldifonso Salinas-Ulloa; Marco Antonio Ponce-Gallegos

doi:10.47487/apcyccv.v5i4.412

Authors

Oyuky Flores-Alamos Departamento de Medicina Interna. Nuevo Hospital Civil de Guadalajara “Dr. Juan I. Menchaca”, Guadalajara, Jalisco, México.
Diego González-Guzmán Departamento de Medicina Interna. Nuevo Hospital Civil de Guadalajara “Dr. Juan I. Menchaca”, Guadalajara, Jalisco, México. https://orcid.org/0009-0009-4248-2136
Antonio de Jesús Andrade-Ortega Departamento de Medicina Interna. Nuevo Hospital Civil de Guadalajara “Dr. Juan I. Menchaca”, Guadalajara, Jalisco, México. https://orcid.org/0000-0001-6796-1445
Jaime Ponce-Gallegos Unidad Cardiológica de Alta Especialidad “Korazón”, Tepic, Nayarit, México. https://orcid.org/0000-0002-5389-2028
Amayrani E. Coyac-Cavazos Unidad de Medicina Académica. Universidad Autónoma de Nayarit, Tepic, Nayarit, México.
César Yldifonso Salinas-Ulloa Departamento de Cardiología Clíni- ca. Instituto Nacional de Cardiología Ignacio Chávez, Juan Badiano 1, Sección XVI, Tlalpan, Ciudad De México, México. https://orcid.org/0000-0003-3737-675X
Marco Antonio Ponce-Gallegos Departamento de Cardiología Clíni- ca. Instituto Nacional de Cardiología Ignacio Chávez, Juan Badiano 1, Sección XVI, Tlalpan, Ciudad De México, México https://orcid.org/0000-0003-4992-9913

DOI:

https://doi.org/10.47487/apcyccv.v5i4.412

Keywords:

Cryptococcus neoformans, Endocarditis, Mycoses, Mitral Valve

Abstract

Infective endocarditis is a disease that affects mainly the endocardial surface of the heart and cardiac valves (native or prosthetic). The main risk factors for developing infective endocarditis are male sex, older age, intracardiac shunts, prosthetic valves, rheumatic, and congenital heart disease, intracardiac devices, intravenous drugs use, immunosuppression, and hemodialysis. Streptococci and Staphylococci spp. have been the most frequent isolated organisms. On the other hand, the most common fungal organism in infective endocarditis is Candida albicans (24-46%), followed by Aspergillus spp. (25%), and a few cases by Cryptococcus neoformans, which are associated with higher rate of mortality. This case provides an interesting case of Cryptococcus neoformans native valve infective endocarditis in a young woman with stage IV chronic kidney disease and severe malnutrition.

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