Acute cardiorenal decompensation in the setting of chronic renal artery stenosis treated with successful renal artery stenting. A case report
DOI:
https://doi.org/10.47487/apcyccv.v6i4.515Keywords:
Renal Artery Obstruction, Hypertension, Pulmonary Edema, Acute Kidney Injury, Angioplasty, BalloonAbstract
Atherosclerotic renal artery stenosis may present with resistant hypertension, hypertensive crisis, ischemic nephropathy, and cardiac destabilization. Although early studies of renal artery stenting showed promise, later trials found no benefit over medical therapy—yet often excluded high-risk, acute cases. We describe an 85-year-old male with cardiovascular risk factors who developed a hypertensive crisis, acute kidney injury, and flash pulmonary edema. An angiogram revealed severe ostial right renal artery stenosis. Stenting resulted in the rapid resolution of the acute crisis and restoration of baseline renal function. This case underscores the potential benefit of revascularization in select high-risk presentations of renal artery stenosis.
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Safian RD. Renal artery stenosis. Prog Cardiovasc Dis. 2021;65:60-70. doi: 10.1016/j.pcad.2021.03.003.
Whelton PK, Carey RM, Aronow WS, Casey DE, Jr., Collins KJ, Dennison Himmelfarb C, et al. 2017 ACC/AHA/AAPA/ABC/ACPM/AGS/APhA/ ASH/ASPC/NMA/PCNA Guideline for the Prevention, Detection, Evaluation, and Management of High Blood Pressure in Adults: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines. Hypertension. 2018;71(6):e13-e115. doi: 10.1161/HYP.0000000000000066.
Pappaccogli M, Robberechts T, Lengele JP, Van der Niepen P, Sarafidis P, Rabbia F, et al. Endovascular Versus Medical Management of Atherosclerotic Renovascular Disease: Update and Emerging Concepts. Hypertension. 2023;80(6):1150-61. doi: 10.1161/ HYPERTENSIONAHA.122.17965.
Ritchie J, Green D, Chrysochou C, Chalmers N, Foley RN, Kalra PA. High-risk clinical presentations in atherosclerotic renovascular disease: prognosis and response to renal artery revascularization. Am J Kidney Dis. 2014;63(2):186-97. doi: 10.1053/j.ajkd.2013.07.020.
Colbert GB, Abra G, Lerma EV. Update and review of renal artery stenosis. Dis Mon. 2021;67(6):101118. doi: 10.1016/j. disamonth.2020.101118.
Schwarz K, Straume Bah I, Will M, Kwok CS, Mascherbauer J, Kumric M, et al. Prevalence and Risk Factors of Renal Artery Stenosis in Patients Undergoing Simultaneous Coronary and Renal Artery Angiography: A Systematic Review and Meta-Analysis of 31,689 Patients from 31 Studies. Diseases. 2024;12(9):208. doi: 10.3390/diseases12090208.
Silverberg D, Menes T, Rimon U, Salomon O, Halak M. Acute renal artery occlusion: Presentation, treatment, and outcome. J Vasc Surg. 2016;64(4):1026-32. doi: 10.1016/j.jvs.2016.04.043.
de Bhailis A, Al-Chalabi S, Hagemann R, Ibrahim S, Hudson A, Lake E, et al. Managing acute presentations of atheromatous renal artery stenosis. BMC Nephrol. 2022;23(1):210. doi: 10.1186/s12882-022-02813-8.
Cooper CJ, Murphy TP, Cutlip DE, Jamerson K, Henrich W, Reid DM, et al. Stenting and medical therapy for atherosclerotic renal-artery stenosis. N Engl J Med. 2014;370(1):13-22. doi: 10.1056/NEJMoa1310753.
Bax L, Woittiez AJ, Kouwenberg HJ, Mali WP, Buskens E, Beek FJ, et al. Stent placement in patients with atherosclerotic renal artery stenosis and impaired renal function: a randomized trial. Ann Intern Med. 2009;150(12):840-8. doi: 10.7326/0003-4819-150-12- 200906160-00119.
Wheatley K, Ives N, Gray R, Kalra PA, Moss JG, et al. Revascularization versus medical therapy for renal-artery stenosis. N Engl J Med. 2009;361(20):1953-62. doi: 10.1056/NEJMoa0905368.
Kumbhani DJ, Bavry AA, Harvey JE, de Souza R, Scarpioni R, Bhatt DL, et al. Clinical outcomes after percutaneous revascularization versus medical management in patients with significant renal artery stenosis: a meta-analysis of randomized controlled trials. Am Heart J. 2011;161(3):622-30 e1. doi: 10.1016/j.ahj.2010.12.006.
Riaz IB, Husnain M, Riaz H, Asawaeer M, Bilal J, Pandit A, et al. Meta-analysis of revascularization versus medical therapy for atherosclerotic renal artery stenosis. Am J Cardiol. 2014;114(7):1116- 23. doi: 10.1016/j.amjcard.2014.06.033.
Li Y, Cui WH, Wang J, Chen X, Zhang C, Zhu LZ, et al. Percutaneous revascularization for atherosclerotic renal artery stenosis: a metaanalysis. Eur Rev Med Pharmacol Sci. 2022;26(19):7007-14. doi: 10.26355/eurrev_202210_29884.
Green D, Ritchie JP, Chrysochou C, Kalra PA. Revascularisation of renal artery stenosis as a therapy for heart failure: an observational cohort study. Lancet. 2015;385 Suppl 1:S11. doi: 10.1016/S0140- 6736(15)60326-9.
Abu-Amer N, Kukuy OL, Kunin M, Holtzman EJ, Rimon U, Dinour D, et al. Treatment of Severe Renal Artery Stenosis with Acute Kidney Injury Requiring Hemodialysis by Percutaneous Transluminal Renal Angioplasty and Stent Implantation. J Vasc Interv Radiol. 2022;33(6):707-14 e2. doi: 10.1016/j.jvir.2022.03.002
Murphy TP, Cooper CJ, Pencina KM, D’Agostino R, Massaro J, Cutlip DE, et al. Relationship of Albuminuria and Renal Artery Stent Outcomes: Results From the CORAL Randomized Clinical Trial (Cardiovascular Outcomes With Renal Artery Lesions). Hypertension. 2016;68(5):1145-52. doi: 10.1161/HYPERTENSIONAHA.116.07744.
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