Cardiopatía coronaria isquémica y tuberculosis: una sindemia inadvertida.Revisión de la literatura y propuesta de manejo

Mauricio Andrés Murillo Moreno; Laura Valentina López Gutiérrez; Eric Edward Vinck; Gustavo Roncancio Villamil; Catalina Gallego Muñoz; Clara Inés Saldarriaga Giraldo

doi:10.47487/apcyccv.v5i2.375

Authors

Mauricio Andrés Murillo Moreno Departamento de Medicina Interna, Universidad CES, Medellín, Colombia. https://orcid.org/0000-0001-7673-4965
Laura Valentina López Gutiérrez Departamento de Cardiología, Clínica Cardio VID, Medellín, Colombia. https://orcid.org/0000-0001-9660-202X
Eric Edward Vinck Departamento de Cirugía Cardiovascular, Clínica Cardio VID, Medellín, Colombia. https://orcid.org/0000-0002-9728-3910
Gustavo Roncancio Villamil Departamento de Enfermedades Infecciosas, Clínica Cardio VID, Medellín, Colombia. https://orcid.org/0000-0002-2677-6398
Catalina Gallego Muñoz Departamento de Cardiología, Clínica Cardio VID, Medellín, Colombia.
Clara Inés Saldarriaga Giraldo Departamento de Cardiología, Clínica Cardio VID, Medellín, Colombia. https://orcid.org/0000-0002-5945-1127

DOI:

https://doi.org/10.47487/apcyccv.v5i2.375

Keywords:

Tuberculosis, Heart failure, Coronary Disease, Myocardial Infarction

Abstract

Tuberculosis is a disease that is increasing and affects about 1/3 of the world’s population. In line with the increase in tuberculosis, cardiovascular disease has had a similar behavior to this group, ischemic coronary heart disease has become the main cause of death worldwide. It could be extracted, based on literature, a relationship between tuberculosis and ischemic coronary heart disease through risk factors in common and from a possible pathophysiological substrate that links them. The presentation of these two entities reported so far is varied: it has been found as a debut of an acute coronary syndrome in patients with active tuberculosis, and the progressive development of coronary atherosclerosis in patients with latent tuberculosis, among others. Given this possible link and the progressive increase in its incidence rates, we can affirm that we are facing an inadvertent syndemia, and their management faces a challenge for the great pharmacological interactions. The purpose of this review is to clarify this possible link, propose an approach to diagnosis as well as supply an algorithm for the treatment of the entire spectrum of coronary heart disease that coexists with tuberculosis according to the currently available literature.

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References

Khan MK, Islam MN, Ferdous J, Alam MM. An Overview on Epidemiology of Tuberculosis. Mymensingh Med J MMJ. 2019;28(1):259-66.

López-López JP, Posada-Martínez EL, Saldarriaga C, Wyss F, Ponte-Negretti CI, Alexander B, et al. Tuberculosis and the heart. J Am Heart Assoc. 2021;10(7). doi: 10.1161/jaha.120.019435.

Natarajan A, Beena PM, Devnikar AV, Mali S. A systemic review on tuberculosis. Indian J Tuberc. 2020;67(3):295-311. doi: 10.1016/j.ijtb.2020.02.005.

Instituto Nacional de Salud. Informe de Evento [Internet]. Bogotá: INS; 2024 [citado 20 de marzo de 2023]. Disponible en: https://www.ins.gov.co/buscador-eventos/Paginas/Info-Evento.aspx

Situación epidemiológica de la tuberculosis en el Perú, 2018-2022. Boletin Epidemiológico del Perú [Internet]. 2023;12(20): [citado 28 de marzo de 2024] Disponible en: https://www.dge.gob.pe/epipublic/uploads/boletin/boletin_202320_28_163316.pdf

Djaharuddin I, Amir M, Qanitha A. Exploring the link between cardiovascular risk factors and manifestations in latent tuberculosis infection: a comprehensive literature review. Egypt Heart J.2023;75(1):43.

Ministerio de Salud de Colombia. Enfermedades cardiovasculares [Internet]. Bogotá: Ministerio de Salud; c2024 [citado 20 de marzo de 2023]. Disponible en: https://www.minsalud.gov.co/salud/publica/PENT/Paginas/enfermedades-cardiovasculares.aspx

Enfermedad cardiovascular. Principal causa de muerte en Colombia. Boletin ONS [Internet]. 2013;1 [citado 20 de marzo de 2023]. Disponible en: https://www.ins.gov.co/Direcciones/ONS/Boletines/boletin_web_ONS/boletin1.html

Wang TK, Wong CF, Au WK, Cheng VC, Wong SS. Mycobacterium tuberculosis sternal wound infection after open heart surgery: a case report and review of the literature. Diagn Microbiol Infect Dis. 2007;58(2):245-9. doi: 10.1016/j.diagmicrobio.2006.11.021.

Tabaja H, Hajar Z, Kanj SS. A review of eleven cases of tuberculosis presenting as sternal wound abscess after open heart surgery. Infect Dis Lond Engl. 2017;49(10):721-7. doi: 10.1080/23744235.2017.1347817.

Kälvegren H, Fridfeldt J, Bengtsson T. The role of plasma adenosine deaminase in chemoattractant-stimulated oxygen radical production in neutrophils. Eur J Cell Biol. 2010;89(6):462-7. doi: 10.1016/j.ejcb.2009.12.004.

Huaman M, Qualls J, Jose S, Jose S, Schmidt S, Mousa A, et al. Mycobacterium bovis Bacille-Calmette-Guérin Infection Aggravates Atherosclerosis. Front Immunol. 2020;11:607957. doi: 10.3389/fimmu.2020.607957.

World Health Organization. TB disease burden [Internet]. Geneva: WHO; 2022 [citado el 2 de junio de 2024]. Disponible en: https://www.who.int/teams/global-tuberculosis-programme/tb-reports/global-tuberculosis-report-2022/tb-disease-burden

Van Eeden S, Leipsic J, Paul Man SF, Sin DD. The relationship between lung inflammation and cardiovascular disease. Am J Respir Crit Care Med. 2012;186(1):11-6. doi: 10.1164/rccm.201203-0455PP.

Khan Y, Shah M, Shahabuddin S. Incidental finding of tuberculous pleural effusion in patient undergoing coronary artery bypass grafting: Case report. Ann Med Surg. 2019;45:110-2. doi: 10.1016/j.amsu.2019.08.001.

Yuan SM. Sternal wound tuberculosis following cardiac operations: a review. Rev Bras Cir Cardiovasc Órgão Of Soc Bras Cir Cardiovasc. 2015;30(4):489-93. doi: 10.5935/1678-9741.20140102.

Tuladhar SM, Noursadeghi M, Boyle JJ, Friedland JS, Hornick P. Tuberculous pericardial effusion after coronary artery bypass graft. Ann Thorac Surg. 2006;82(4):1519-21. doi: 10.1016/j. athoracsur.2006.02.059.

Wang TK, Wong CF, Au WK, Cheng VC, Wong SS. Mycobacterium tuberculosis sternal wound infection after open heart surgery: a case report and review of the literature. Diagn Microbiol Infect Dis. 2007;58(2):245-9. doi: 10.1016/j.diagmicrobio.2006.11.021.

Ng CSH, Arifi AA, Wan S, Lee TW, Yim APC. Cardiac operation with associated pulmonary resection: a word of caution. Asian Cardiovasc Thorac Ann. 2002;10(4):362-4. doi: 10.1177/021849230201000423.

Bakalli A, Osmani B, Kamberi L, Pllana E. Acute myocardial infarction and pulmonary tuberculosis in a young female patient: a case report. Cases J. 2008;1:246. doi: 10.1186/1757-1626-1-246.

Chan S. An unusual case of mycobacterium tuberculous coronary arteritis and thrombosis resulting in acute myocardial infarction. Forensic Sci Med Pathol. 2018;14(3):390-4. doi: 10.1007/s12024-018-0002-y.

Peddle L, Otto M. Coronary artery tuberculosis: An unusual case of sudden death. Leg Med Tokyo Jpn. 2018;30:56-8. doi: 10.1016/j.legalmed.2017.11.008.

Khalil MW, Grech ED, Al-Mohammed A, Cooper GJ, Sarkar PK. Rapid development of fatal TB constrictive pericarditis after cardiac surgery. J Card Surg. 2006;21(4):417-8. doi: 10.1111/j.1540-8191.2006.00259.x.

Huaman MA, Ticona E, Miranda G, Kryscio RJ, Mugruza R, Aranda E, et al. The Relationship Between Latent Tuberculosis Infection and Acute Myocardial Infarction. Clin Infect Dis Off Publ Infect Dis Soc Am. 2018;66(6):886-92. doi: 10.1093/cid/cix910.

Barreto-Neto N, Segre AW, Guedes LKN, Seguro LPC, Pereira RMR. Resolution of coronary arteritis following tuberculosis treatment. J Clin Tuberc Mycobact Dis. 2022;26:100295. doi: 10.1016/j.jctube.2021.100295

Baluku JB, Nabwana M, Nalunjogi J, Muttamba W, Mubangizi I, Nakiyingi L, et al. Cardiovascular risk factors among people with drug-resistant tuberculosis in Uganda. BMC Cardiovascular Disorders. 2022;22(1):464. doi: 10.1186/s12872-022-02889-y.

Adhikary D, Barman S, Ranjan R, Stone H. A Systematic Review of Major Cardiovascular Risk Factors: A Growing Global Health Concern. Cureus. 2022;14(10):e30119. doi: 10.7759/cureus.30119.

Basham CA, Smith SJ, Romanowski K, Johnston JC. Cardiovascular morbidity and mortality among persons diagnosed with tuberculosis: A systematic review and meta-analysis. PLoS One. 2020;15(7):e0235821. doi: 10.1371/journal.pone.0235821.

Rota S, Rota S. Mycobacterium tuberculosis complex in atherosclerosis. Acta Med Okayama. 2005;59(6):247-51. doi: 10.18926/AMO/31958.

Nezami N, Ghorbanihaghjo A, Rashtchizadeh N, Argani H, Tafrishinejad A, Ghorashi S, et al. Atherogenic changes of low-density lipoprotein susceptibility to oxidation, and antioxidant enzymes in pulmonary tuberculosis. Atherosclerosis. 2011;217(1):268-73. doi: 10.1016/j.atherosclerosis.2011.03.025.

Sumbal A, Sheikh SM, Ikram A, Amir A, Sumbal R, Saeed AR. Latent Tuberculosis Infection (LTBI) as a predictor of coronary artery disease: A systematic review and meta-analysis. Heliyon. 2023;9(4):e15365. doi: 10.1016/j.heliyon.2023.e15365

Li Y, Wu Q, Chen Y. Myocardial infarction and tuberculosis. Acta Cardiol. 2012;67(3):371-2. doi: 10.1080/ac.67.3.2160732.

Majumdar G, Agarwal SK, Pande S, Chandra B, Tewari P. A Case Report of Combined Radical Pericardiectomy and Beating Heart Coronary Artery Bypass Grafting in a Patient with Tubercular Chronic Constrictive Pericarditis with Coronary Artery Disease. Ann Card Anaesth. 2017;20(4):465-7. doi: 10.4103/aca.ACA_102_17.

Farid NA, Jakubowski JA, Payne CD, Li YG, Jin Y, Ernest II CS, et al. Effect of rifampin on the pharmacokinetics and pharmacodynamics of prasugrel in healthy male subjects. Curr Med Res Opin. 2009;25(8):1821-9. doi: 10.1185/03007990903018360.

Teng R, Mitchell P, Butler K. Effect of rifampicin on the pharmacokinetics and pharmacodynamics of ticagrelor in healthy subjects. Eur J Clin Pharmacol. 2013;69(4):877-83. doi: 10.1007/s00228-012-1436-x.

Judge HM, Patil SB, Buckland RJ, Jakubowski JA, Storey RF. Potentiation of clopidogrel active metabolite formation by rifampicin leads to greater P2Y12 receptor blockade and inhibition of platelet aggregation after clopidogrel. J Thromb Haemost JTH.2010;8(8):1820-7. doi: 10.1111/j.1538-7836.2010.03925.x.

Mendell J, Chen S, He L, Desai M, Parasramupria DA. The Effect of Rifampin on the Pharmacokinetics of Edoxaban in Healthy Adults. Clin Drug Investig. 2015;35(7):447-53. doi: 10.1007/s40261-015-0298-2.

Härtter S, Koenen-Bergmann M, Sharma A, Nehmiz G, Lemke U, Timmer W, et al. Decrease in the oral bioavailability of dabigatran etexilate after co-medication with rifampicin. Br J Clin Pharmacol. 2012;74(3):490-500. doi: 10.1111/j.1365-2125.2012.04218.x.

Vakkalagadda B, Frost C, Byon W, Boyd RA, Wang J, Zhang D, et al. Effect of Rifampin on the Pharmacokinetics of Apixaban, an Oral Direct Inhibitor of Factor Xa. Am J Cardiovasc Drugs Drugs Devices Interv. 2016;16(2):119-27. doi: 10.1007/s40256-015-0157-9.

Paul P. Dobesh, Zachary A. Stacy, Chapter 2 - Pharmacology of Oral Anticoagulants. In: Flaker G. Stroke Prevention in Atrial Fibrillation. Elsevier; 2019. p. 11-34. doi: 10.1016/B978-0-323-55429-9.00002-9.

Steffel J, Collins R, Antz M, Cornu P, Desteghe L, Haeusler KG, et al. 2021 European Heart Rhythm Association Practical Guide on the Use of Non-Vitamin K Antagonist Oral Anticoagulants in Patients with Atrial Fibrillation. EP Eur. 2021;23(10):1612-76. doi: 10.1093/europace/euab065.

Lee HJ, Kim HK, Kim BS, Han KD, Park CS, Rhee TM, et al. Safety and effectiveness of anticoagulation with non-vitamin K antagonist oral anticoagulants and warfarin in patients on tuberculosis treatment. Sci Rep. 2023;13:2060. doi: 10.1038/s41598-023-29185-9.

Lobato LS, Rosa PS, Ferreira J da S, Neumann A da S, da Silva MG, do Nascimento DC, et al. Statins Increase Rifampin Mycobactericidal Effect. Antimicrob Agents Chemother. 2014;58(10):5766-74. doi: 10.1128/AAC.01826-13.

Cross GB, Sari IP, Kityo C, Lu Q, Pokharkar Y, Moorakonda RB, et al. Rosuvastatin adjunctive therapy for rifampicin-susceptible pulmonary tuberculosis: a phase 2b, randomised, open-label, multicentre trial. Lancet Infect Dis. 2023;23(7):847-55. doi: 10.1016/S1473-3099(23)00067-1.

Backman JT, Luurila H, Neuvonen M, Neuvonen PJ. Rifampin markedly decreases and gemfibrozil increases the plasma concentrations of atorvastatin and its metabolites. Clin Pharmacol Ther. 2005;78(2):154-67. doi: 10.1016/j.clpt.2005.04.007.

Kyrklund C, Backman JT, Kivistö KT, Neuvonen M, Laitila J, Neuvonen PJ. Rifampin greatly reduces plasma simvastatin and simvastatin acid concentrations. Clin Pharmacol Ther. 2000;68(6):592-7. doi: 10.1067/mcp.2000.111414.

McDonagh TA, Metra M, Adamo M, Gardner RS, Baumbach A, Böhm M, et al. 2021 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure. Eur Heart J. 2021;42(36):3599-726. doi: 10.1093/eurheartj/ehab368.

Agrawal A, Agarwal SK, Kaleekal T, Gupta YK. Rifampicin and antihypertensive drugs in chronic kidney disease: Pharmacokinetic interactions and their clinical impact. Indian J Nephrol. 2016;26(5):322-8. doi: 10.4103/0971-4065.176145.

Liu W, Yan T, Chen K, Yang L, Benet LZ, Zhai S. Predicting Interactions between Rifampin and Antihypertensive Drugs Using the Biopharmaceutics Drug Disposition Classification System. Pharmacotherapy. 2020;40(4):274-90. doi.org/10.1002/phar.2380

Pathways and Guidelines Development Subgroup SACUBITRIL/VALSARTAN (ENTRESTO®) HEART FAILURE INFORMATION FOR PRIMARY CARE [Internet]. Available from: https://gmmmg.nhs.uk/wp-content/uploads/2021/09/Sacubitril-Valsartan-info-sheet-for-GPs-Sep-2021-FINAL.pdf

Kasichayanula S, Liu X, Griffen SC, Lacreta FP, Boulton DW. Effects of rifampin and mefenamic acid on the pharmacokinetics and pharmacodynamics of dapagliflozin. Diabetes Obes Metab. 2013;15(3):280-3. doi: 10.1111/dom.12024.

Macha S, Koenen R, Sennewald R, Schöne K, Hummel N, Riedmaier S, et al. Effect of gemfibrozil, rifampicin, or probenecid on the pharmacokinetics of the SGLT2 inhibitor empagliflozin in healthy volunteers. Clin Ther. 2014;36(2):280-290.e1. doi: 10.1016/j.clinthera.2014.01.003.