Mechanical complications after myocardial infarction in a National Reference Hospital
DOI:
https://doi.org/10.47487/apcyccv.v3i1.200Keywords:
Myocardial infarction, Heart Rupture, Post-Infarction, Ventricular Septal RuptureAbstract
Objective. To determine the clinical characteristics, therapeutic and in-hospital mortality of patients with mechanical complications post myocardial infarction. Materials and methods. Observational, descriptive and retrospective study. We included patients >18 years old with a diagnosis of mechanical complication post myocardial infarction hospitalized at the Instituto Nacional Cardiovascular- INCOR in Lima -Peru, from January 1, 2017 to December 31, 2021. Variables like clinical characteristics, treatments, complications, and in-hospital mortality were studied. Results. We found 37 cases, with a predominance of males (73.0%) and a median age of 73 years old. The location of the myocardial infarction was 51.4% in the anterior wall and 43.2% in the inferior wall. The patients received reperfusion therapy with fibrinolysis in 5 cases (13.5%), coronary angioplasty in 5 (13.5%), and 73% received only medical management prior to the diagnosis of mechanical complications. Of the 37 patients, 13 (35.1%) presented isolated ventricular free wall rupture, 12 (32.4%) isolated interventricular septum rupture, 10 (27.0%) the combination of ventricular free wall rupture and interventricular septum, and 2 (5.4%) papillary muscle rupture. In-hospital mortality was 51.4%. Conclusions. The ventricular free wall rupture was the most frequent complication, patients with mechanical complications after myocardial infarction still maintain high intra-hospital mortality rates, mainly in those who did not have adequate surgical treatment.
Downloads
References
Khan MA, Hashim MJ, Mustafa H, Baniyas MY, Al Suwaidi SKBM, AlKatheeri R, Alblooshi FMK, Almatrooshi MEAH, Alzaabi MEH, Al Darmaki RS, Lootah SNAHet al. Global Epidemiology of Ischemic Heart Disease: Results from the Global Burden of Disease Study. Cureus. 2020 Jul 23;12(7):e9349. doi: 10.7759/cureus.9349.
Kristensen SD, Laut KG, Fajadet J, Kaifoszova Z, Kala P, Di Mario C, et al. Reperfusion therapy for ST elevation acute myocardial infarction 2010/2011: current status in 37 ESC countries. Eur Heart J. 2014 Aug 1;35(29):1957-70. doi: 10.1093/eurheartj/eht529.
Navarro-Cuartero J, Córdoba-Soriano JG, Jiménez-Mazuecos J, Gutiérrez-Díez A, Gallardo-López A, Melehi D. Incidence and Prognosis of Mechanical Complications of STEMI After Primary Angioplasty: Data From a Single-center Registry of an Infarction Code Program. Rev Esp Cardiol (Engl Ed). 2016 Sep;69(9):874-6. English, Spanish. doi: 10.1016/j.rec.2016.04.032.
Honda S, Asaumi Y, Yamane T, Nagai T, Miyagi T, Noguchi T, et al. Trends in the clinical and pathological characteristics of cardiac rupture in patients with acute myocardial infarction over 35 years. J Am Heart Assoc. 2014 Oct 20;3(5):e000984. doi: 10.1161/JAHA.114.000984.
Figueras J, Alcalde O, Barrabés JA, Serra V, Alguersuari J, Cortadellas J, Lidón RM. Changes in hospital mortality rates in 425 patients with acute ST-elevation myocardial infarction and cardiac rupture over a 30-year period. Circulation. 2008 Dec 16;118(25):2783-9. doi: 10.1161/CIRCULATIONAHA.108.776690.
Elbadawi A, Elgendy IY, Mahmoud K, Barakat AF, Mentias A, Mohamed AH, et al. Temporal Trends and Outcomes of Mechanical Complications in Patients With Acute Myocardial Infarction. JACC Cardiovasc Interv. 2019 Sep 23;12(18):1825-1836. doi: 10.1016/j.jcin.2019.04.039.
Damluji AA, van Diepen S, Katz JN, Menon V, Tamis-Holland JE, Bakitas M, Cohen MG, Balsam LB, Chikwe J; American Heart Association Council on Clinical Cardiology; Council on Arteriosclerosis, Thrombosis and Vascular Biology; Council on Cardiovascular Surgery and Anesthesia; and Council on Cardiovascular and Stroke Nursinget al. Mechanical Complications of Acute Myocardial Infarction: A Scientific Statement From the American Heart Association. Circulation. 2021 Jul 13;144(2):e16-e35. doi: 10.1161/CIR.0000000000000985.
Gong FF, Vaitenas I, Malaisrie SC, Maganti K. Mechanical Complications of Acute Myocardial Infarction: A Review. JAMA Cardiol. 2021 Mar 1;6(3):341-349. doi: 10.1001/jamacardio.2020.3690.
Gueret P, Khalife K, Jobic Y, Fillipi E, Isaaz K, Tassan-Mangina S, Baixas C, Motreff P, Meune C; Study Investigatorset al. Echocardiographic assessment of the incidence of mechanical complications during the early phase of myocardial infarction in the reperfusion era: a French multicentre prospective registry. Arch Cardiovasc Dis. 2008 Jan;101(1):41-7. doi: 10.1016/s1875-2136(08)70254-7.
Caballero-Borrego J, Hernández-García JM, Sanchis-Fores J. Complicaciones mecánicas en el infarto agudo de miocardio. ¿Cuáles son, cuál es su tratamiento y qué papel tiene el intervencionismo percutáneo? Rev Esp Cardiol. 1 de noviembre de 2009;9:62-70. DOIdoi: 10.1016/S1131-3587(09)72814-6.
Kilic A, Sultan I, Chu D, Wang Y, Gleason TG. Mitral Valve Surgery for Papillary Muscle Rupture: Outcomes in 1342 Patients From The Society of Thoracic Surgeons Database. Ann Thorac Surg. 2020 Dec;110(6):1975-1981. DOIdoi: 10.1016/j.athoracsur.2020.03.097.
Bhardwaj B, Sidhu G, Balla S, Kumar V, Kumar A, Aggarwal K, Dohrmann ML, Alpert MAet al. Outcomes and Hospital Utilization in Patients With Papillary Muscle Rupture Associated With Acute Myocardial Infarction. Am J Cardiol. 2020 Apr 1;125(7):1020-1025. doi: 10.1016/j.amjcard.2019.12.051.
Calvert PA, Cockburn J, Wynne D, Ludman P, Rana BS, Northridge DCalvert PA, Cockburn J, Wynne D, et al. Percutaneous closure of postinfarction ventricular septal defect: in-hospital outcomes and long-term follow-up of UK experience. Circulation. 2014;129(23):2395-402. DOIdoi: 10.1161/CIRCULATIONAHA.113.005839.
Goldsweig AM, Wang Y, Forrest JK, Cleman MW, Minges KE, Mangi AA, et al. Ventricular septal rupture complicating acute myocardial infarction: Incidence, treatment, and outcomes among medicare beneficiaries 1999-2014. Catheter Cardiovasc Interv Off J Soc Card Angiogr Interv. 15 de noviembre de 2018;92(6):1104-15.Goldsweig AM, Wang Y, Forrest JK, Cleman MW, Minges KE, Mangi AA, et al. Ventricular septal rupture complicating acute myocardial infarction: Incidence, treatment, and outcomes among medicare beneficiaries 1999-2014. Catheter Cardiovasc Interv Off J Soc Card Angiogr Interv. 2018;92(6):1104-15. DOIdoi: 10.1002/ccd.27576.
Koklu E, Arslan S, Yuksel IO, Bayar N, Yilmaz GM, Kucukseymen S. Management of Left Ventricular Free Wall Rupture Associated with Acute Myocardial Infarction. J Acute Med. 1 de marzo de 2017;7(1):31-4.Koklu E, Arslan S, Yuksel IO, Bayar N, Yilmaz GM, Kucukseymen S. Management of Left Ventricular Free Wall Rupture Associated with Acute Myocardial Infarction. J Acute Med. 1 de marzo de 2017;7(1):31-4. DOIdoi: 10.6705/j.jacme.2017.0701.005.
Prifti E, Bonacchi M, Baboci A, Giunti G, Veshti A, Demiraj A, et al. Surgical treatment of post-infarction left ventricular pseudoaneurysm: Case series highlighting various surgical strategies. Ann Med Surg. 9 de marzo de 2017;16:44-51.Prifti E, Bonacchi M, Baboci A, Giunti G, Veshti A, Demiraj A, et al. Surgical treatment of post-infarction left ventricular pseudoaneurysm: Case series highlighting various surgical strategies. Ann Med Surg. 2017;16:44-51. DOIdoi: 10.1016/j.amsu.2017.03.013.
Sanmartín-Fernández M, Raposeiras-Roubin S, Anguita-Sánchez M, Marín F, Garcia-Marquez M, Fernández-Pérez C, et al. In-hospital outcomes of mechanical complications in acute myocardial infarction: Analysis from a nationwide Spanish database. Cardiol J. 2021;28(4):589-97. DOIdoi: 10.5603/CJ.a2020.0181.
Magalhães P, Mateus P, Carvalho S, Leão S, Cordeiro F, Moreira JI. Relationship between treatment delay and type of reperfusion therapy and mechanical complications of acute myocardial infarction. Eur Heart J Acute Cardiovasc Care. 2016;5(5):468-74. DOIdoi: 10.1177/2048872616637038.
Lanz J, Wyss D, Räber L, Stortecky S, Hunziker L, Blöchlinger S, et al. Mechanical complications in patients with ST-segment elevation myocardial infarction: A single centre experience. PLoS One. 2019;14(2):e0209502. DOIdoi: 10.1371/journal.pone.0209502.
Puerto E, Viana-Tejedor A, Martínez-Sellés M, Domínguez-Pérez L, Moreno G, Martín-Asenjo R, et al. Temporal Trends in Mechanical Complications of Acute Myocardial Infarction in the Elderly. J Am Coll Cardiol. 2018;72(9):959-66. DOIdoi: 10.1016/j.jacc.2018.06.031.
Peiyuan H, Jingang Y, Haiyan X, Xiaojin G, Ying X, Yuan W, et al. The Comparison of the Outcomes between Primary PCI, Fibrinolysis, and No Reperfusion in Patients ≥ 75 Years Old with ST-Segment Elevation Myocardial Infarction: Results from the Chinese Acute Myocardial Infarction (CAMI) Registry. PLoS One. 2016;11(11):e0165672. DOIdoi: 10.1371/journal.pone.0165672.
Lawton JS, Tamis-Holland JE, Bangalore S,Bates ER, Beckie TM, Bischoff JM, et al. 2021 ACC/AHA/SCAI Guideline for Coronary Artery Revascularization: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines. J Am Coll Cardiol. 2022;79(2):e21-e129. DOIdoi: 10.1016/j.jacc.2021.09.006.
Ibanez B, James S, Agewall S, Antunes MJ, Bucciarelli-Ducci C, Bueno H, et al. 2017 ESC Guidelines for the management of acute myocardial infarction in patients presenting with ST-segment elevation: The Task Force for the management of acute myocardial infarction in patients presenting with ST-segment elevation of the European Society of Cardiology (ESC). Eur Heart J. 2018;39(2):119-77. DOIdoi: 10.1093/eurheartj/ehx393.
Arnaoutakis GJ, Zhao Y, George TJ, Sciortino CM, McCarthy PM, Conte JV. Surgical repair of ventricular septal defect after myocardial infarction: outcomes from the Society of Thoracic Surgeons National Database. Ann Thorac Surg. 2012;94(2):436-43. DOIdoi: 10.1016/j.athoracsur.2012.04.020.