Is protected PCI truly protective? Critical reflections following CHIPBCIS3 and previous evidence

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DOI:

https://doi.org/10.47487/apcyccv.v7i2.633

Palabras clave:

Percutaneous Coronary Intervention, Heart-Assist Devices, Coronary Artery Disease, Myocardial Revascularization, Ventricular Function, Left

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Referencias

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O’Neill WW, Kleiman NS, Moses J, Henriques JP, Dixon S, Massaro J, et al. A prospective, randomized clinical trial of hemodynamic support with Impella 2.5 versus intraaortic balloon pump in patients undergoing high-risk percutaneous coronary intervention: the PROTECT II study. Circulation. 2012;126(14):1717-27. doi: 10.1161/ CIRCULATIONAHA.112.098194.

Perera D, Stables R, Thomas M, Booth J, Pitt M, Blackman D, et al. Elective intra-aortic balloon counterpulsation during high-risk percutaneous coronary intervention: a randomized controlled trial. JAMA. 2010;304(8):867-74. doi: 10.1001/jama.2010.1190

Di Pietro G, Improta R, De Filippo O, et al. Systematic review and meta-analysis of short-term outcomes in patients following protected high-risk PCI. Am J Cardiol. 2016;258:172–179.

Vetrovec GW, Kaki A, Dahle TG. A review of bleeding risk with Impella-supported high-risk percutaneous coronary intervention. Heart Int. 2020;14:92–99.

Asleh R, Resar J. Utilization of Percutaneous Mechanical Circulatory Support Devices in Cardiogenic Shock Complicating Acute Myocardial Infarction and High-Risk Percutaneous Coronary Interventions. J Clin Med. 2019;8:1209. doi:10.3390/ jcm8081209

Stretch R, Sauer CM, Yuh DD, Bonde P. National trends in the utilization of short-term mechanical circulatory support: incidence, outcomes, and cost analysis. J Am Coll Cardiol. 2014;64:1407–1415. doi:10.1016/j.jacc.2014.07.958

Dhruva SS, Ross JS, Mortazavi BJ, et al. Association of Use of an Intravascular Microaxial Left Ventricular Assist Device vs Intra-aortic Balloon Pump With In-Hospital Mortality and Major Bleeding Among Patients With Acute Myocardial Infarction Complicated by Cardiogenic Shock. JAMA. 2020;323:734–745. doi:10.1001/jama.2020.0254

Lombardi M, Chiabrando J, Ameri P, et al. Left ventricular functional recovery after complex high-risk indicated percutaneous coronary intervention supported with microaxial flow pump. J Cardiovasc Med. 2025;26:575–581. doi:10.2459/JCM.00001786

Azzalini L, Seth M, Sukul D, Arora DS, Chattahi J, Osman A, et al. Impact of Left Ventricular End-Diastolic Pressure on the Outcomes of Patients Undergoing Percutaneous Coronary Intervention. Am J Cardiol. 2022;185:107-114. doi: 10.1016/j.amjcard.2022.09.007.

Maznyczka AM, McCartney PJ, Oldroyd KG, Lindsay M, McEntegart M, Eteiba H, et al. Risk Stratification Guided by the Index of Microcirculatory Resistance and Left Ventricular End-Diastolic Pressure in Acute Myocardial Infarction. Circ Cardiovasc Interv. 2021;14(2):e009529. doi: 10.1161/ CIRCINTERVENTIONS.120.009529.

Leick J, Gjata A, Pulz J, Weisbarth T, Richter K, Krause T, et al. Evaluation of LVEDP Change During High-Risk PCI With and Without Impella Support (ELVIS)—A Pilot Trial. J Clin Med. 2025;14(3):824. doi: 10.3390/jcm14030824.

Shah R, Nayyar M, Le F, et al. A meta-analysis of optimal medical therapy with or without percutaneous coronary intervention in patients with stable coronary artery disease. Coron Artery Dis. 2021;33:91–97. doi:10.1097/MCA.0000000000001041

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Kayali F, Tahhan O, Vecchio G, Jubouri M, Noubani JM, Bailey DM, et al. Left ventricular unloading to facilitate ventricular remodelling in heart failure: A narrative review of mechanical circulatory support. Exp Physiol. 2024;109(11):1826-1836. doi: 10.1113/EP091796

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27-05-2026

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